There are a lot of hidden costs involved sometimes forgotten about at the initial planning.
It may get frustrating not be able to identify a certain scenic spot, building, etc and missing others while concentrating on driving in an unfamiliar environment.
You do have to be well prepared to ensure that your holiday will be worth-it.
There are hazards involved such as getting lost in dangerous areas, not knowing that you are in such an area and not having input from a professional as to local customs, etc.
Driving on the ‘wrong’ (left) side of the road needs constant concentration for those use to driving on the right-hand side of the road. However, vigilance and a bit of familiarization of the rules and local customs of the road before arrival will go a long way easing such stress.